Luca (Stefano Accorsi) is an idealistic surgeon working at a humanitarian clinic in Kenya. Struggling with resource shortages and operational demands, he reaches out for help to his longtime friend Mario (Pierfrancesco Favino), a wealthy and successful surgeon based in Rome. Mario arrives in Africa carrying medical supplies, but he is actually fleeing personal and legal trouble back home involving corruption. Complications escalate with the arrival of Ginevra (Vittoria Puccini), a woman who was once Luca's love interest but is now married to Mario, reigniting a complex romantic triangle, professional rivalries, and moral compromises amid the harsh realities of their environment.